Analysis of wind energy - Free Essay Example

Sample details Pages: 5 Words: 1649 Downloads: 2 Date added: 2019/08/08 Category Energy Industry Essay Level High school Tags: Wind Energy Essay Did you like this example? The advancement in technology which led to industrialization over the last century has resulted in geometric increase in population. Breakthrough in the field of medicine and other technologies subsequently improved fertility, rise in life expectancy and rise in standard of living. The baby boom era saw an unprecedented rise in population from 2.1 billion to over 6.5 billion and the population is expected to rise to about 9 billion people by year 2050 (United nations,2006). This increase in population has led to increase in demand for energy. This has resulted in the burning of more fossil fuels which has raised lots of concerns. The first concern being the question of sustainability due to fossil fuel being non-renewable and the second being the issue of global warming. Don’t waste time! Our writers will create an original "Analysis of wind energy" essay for you Create order With population set to be on the rise, demand for electricity and other energy sources is bound to increase, more cars begin to ply our roads as more people need to move from one place to the other. These means the rate at which we consume fossil fuel increases as well. This increases the fear of running out of fossil fuel someday questions the sustainability of fossil fuel. The bye products of combusting fossil fuel has also been having derogatory effects on our environment. The release of Carbon monoxide into the atmosphere has contributed to the increase in greenhouse gases. This has resulted in an increase in the average temperature of the earth surface and subsequently contributed to the climate change we are experiencing. Renewable energy sources has been identified as the solution to these problems. Renewable energy sources include solar energy, wind energy, biomass, geothermal energy, hydroelectric power among others. All these sources are renewable and at no risk of running out. Also, unlike fossil fuel, they are environmentally friendly as they contribute little or nothing to the greenhouse gases. According to the U.S. Energy Information and Administration, Renewable energy accounted for 12.7 percent of the total primary energy production in 2017. About 77.6 percent came from fossil fuel (2018). However, renewable energies have various limitations which affects their contribution to energy production. Among these limitations are technological limitations, economic limitations and environmental limitations. In this paper, the limitations of Wind energy will be discussed and probable solutions will be proposed. WIND ENERGY Wind energy is the kinetic energy due to airflow. This airflow is a result of the uneven heating of the earths surface by the sun. The difference in the rate causes the movement of air, as the hot air rises and the cold air goes opposite way in other to reach an equilibrium. The energy in the wind is harnessed by using a Wind Turbine which captures the kinetic energy in the wind. The kinetic energy in the wind causes the blades of the turbine to rotate here by creating a mechanical energy which turns a shaft connected to a gear box. Depending on the gearbox configuration, the speed of rotation of the shaft is multiplied by a factor of 100 or more which in turn drives a generator that produces electricity. Since the Energy crises in 1973, Wind energy has been identified as one of the economically viable renewable energy. Countries like Denmark, Sweden, China, and USA among others have invested heavily in the technology that converts wind energy to electrical energy. This has reduced the cost of per Kw hour of electricity generated by wind by about 80%. However, electricity from wind energy is still more costly than energy generated by fossil fuel. This is due to the high cost of setting up a wind farm as well as running cost. Wind turbines have potential for high efficiency , low operating costs , zero carbon dioxide emission and it only takes the wind turbine about 25 percent of its age to break even and produce the energy that goes into producing, operating and recycling the it (Rose mary P.J, 2014). There are a few things that can be done to reduce the cost of per KW of electricity generated from wind energy. We can improve the technology to produce more electricity at the same cost or reduced cost by trying to eliminate exergy destruction in the system. We can also make policies that help to reduce the running cost of wind turbines. Policies such as reduced tax and incentives for investing in wind turbines. ECONOMICS OF WIND ENERGY The cost of wind energy per KW hour depends on lots of factors ranging from wind speed, location, type of wind turbine. A study done by Raghed showed that the cost of electricity generated in wind power mainly depends on capital and investment cost, operation and maintenance cost and fuel cost. A closer look into the cost of electricity per KW hour in wind energy shows that the cost depends on other things such as the economic depreciation of the capital equipment, interest paid on initial loans, taxes, government incentives and tax credits, electricity bills while on standby, wind speed among others (Ragheb, 2017). This factors vary from location to location. The cost of leasing land for wind farms in the Middle West is less than the cost of leasing the same land mass in the north east coast or in southern states like Texas or California. However the wind speed is more favorable in the Midwestern states than the North east coast and the aforementioned southern states. Other factors that contribute to the cost of wind energy per KW hour is the type of turbine. Different turbines have different efficiencies at different wind speeds. The height of the hub and the diameter of the wind turbines also play a key role in the output of the wind turbine (Rose, 2014). Due to all these factors, it is difficult to specifically pinpoint a particular cost for wind energy as these factors vary from one location to another but one fact that has been ascertained is that the cost of electricity generated per KW hour from wind energy is more than that generated from fossil fuels hereby making it less competitive in the market. However, there are various policies that has been implemented to offset some of these costs, hence making wind energy more profitable for investors. Federal policies like the Production Tax Credit (PTC), Renewable Energy Production Incentive (REPI), and Modified Accelerated Cost-Recovery System (MACRS) among others have been initiated over the years. This has resulted in increase in the installed capacity of the wind power. It was recorded that the installed capacity grew by about 35% in 2005 when the PTC was reinstated after the PTC expired in 2004 (Ragheb, 2017). The policies discussed above has encouraged investors to invest in renewable energy but there has not really being a federal move to reduce dependency on cheaper fossil fuel. Elisabeth Rosenthal in an article for the New York Times in 2010 wrote that If the United States is to catch up to countries like Portugal, the United States must overcome obstacles like a fragmented, outdated energy grid poorly suited to renewable en ergy, a historic reliance on plentiful and cheap supplies of fossil fuels, especially coal, powerful oil and coal industries that often oppose incentives for renewable development and an energy policy that is influenced by individual states. The federal government must improve the energy grids to be more renewable energy friendly to reduce the cost of transporting the energy. The federal government should also reduce the incentives on electricity from fossil fuel and allocate more of the funds to renewable energy. EXERGY ANALYSIS OF WIND TURBINE Exergy is the useful energy in a system. It is the energy available for useful work. It can be referred to as the dollars in a generating plant as it is the energy available for sale. Although the wind power energy has been ascertained to have high efficiency potentials, the wind turbine can only harvest a small portion of the kinetic energy in the wind. To increase the quantity of energy resources harvested from the wind, a set of turbines which forms a wind farm are strategically located on a field. The set of turbines are connected to a grid to transport the energy to distribution centers. The performance of the wind farm depends on wind speed, wake effects which depends on the spacing between the turbines as well as the topography of the field. In other to maximize the efficiency of the wind farm hereby optimizing power production, the turbines must be positioned at a distance from each other. This distance must be sufficient for the wake effects to diminish and the wind to recov er from the energy harvested from it by the turbine ahead of it (Hui, 2015). For individual wind turbines, the exergy efficiency is a measure of how well the stream exergy of the wind is converted into useful turbine work output which is converted to electricity or used to do work. (ozgener and ozgener, 2006, Reynaga et al, 2017). The input exergy of a wind turbine is dependent on the mass of air causing the blades to rotate. Exergy depends on the dead state and the only difference between the wind at a point and dead state is the velocity it possesses when it is not in dead state. This velocity gives it its kinetic energy which can be converted to useful work by the wind turbine. Irrespective of the temperature and pressure, the energy input of the wind turbine is dependent on the velocity of the wind (Ozgener and Ozgener, 2006). The maximum amount of power available to the wind turbine is equal to the product of the mass flow rate of the air and the specific exergy of the air. The output exergy is equal to the exergy available at the inverter. The exergy de struction is the difference between the output exergy and the input exergy. Sources of exergy destruction in the wind turbine includes heat, friction and noise. And these losses occur during the mechanical (shaft speed multiplication and braking) and electrical (generators) activities of the wind turbine.

The Management and Control of Quality 8e - 34169 Words

http://www.helpyoustudy.info CHAPTER 1 INTRODUCTION TO QUALITY TRUE/FALSE QUESTIONS 1. In the early Twentieth century, the artificial separation of production workers from responsibility for quality assurance led to an increased focus on quality among both workers and their managers. Answer: F AACSB: Analytic Skills The measure of efficiency defined as the amount of output achieved per unit of input is referred to as productivity. Answer: T AACSB: Reflective Thinking Skills Management control refers to any planned and systematic activity directed toward providing consumers with products of appropriate quality, along with the confidence that products meet consumers’ requirements. Answer: F AACSB: Analytic Skills The transcendent†¦show more content†¦d. global quality time and motion guidelines standards; workforce orientation and commitment. Answer: a AACSB: Analytic Skills 2. Page 3 of 26 http://www.helpyoustudy.info http://www.helpyoustudy.info 3. A key contribution of Frederick Taylor’s scientific management philosophy was to: a. reduce the reliance on inspectors for quality assurance. b. increase the training and education workers received. c. separate the planning function from the execution function. d. combine individual work tasks to promote teamwork. Answer: c AACSB: Analytic Skills 4. The change in society’s attitude from â€Å"let the buyer beware† to â€Å"let the producer beware† was fuelled by all the following factors EXCEPT: a. government safety regulations. b. product recalls. c. popularity of TQM as a quality tool. d. the rapid increase in product-liability judgments. Answer: c AACSB: Reflective Thinking Skills Which of the following is most appropriate in describing the quality efforts undertaken with the scientific management philosophy? a. Defect prevention was emphasized. b. Quality circles were extensively used. c. Use of inspection was wide-spread. d. Quality was every worker’s responsibility. 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Cultural Dimensions In Advertising Free Essays

SCHOOL OF COMMUNICATION CMNS 323-4 (W)* (D100) Instructor:Brad KingSpring Semester 2012 Email: bka10@sfu. ca Burnaby Day Twitter: @btcking ————————————————- CULTURAL DIMENSIONS IN ADVERTISING Prerequisites: 60 units, including two of CMNS 220, 221, 223 or 226. CMNS 362 or 363 is strongly recommended. We will write a custom essay sample on Cultural Dimensions In Advertising or any similar topic only for you Order Now Overview: Advertising is everywhere in contemporary society. From television and the Internet, to newspapers and magazines, people are exposed to thousands of advertising ‘impressions’ every day. Beyond individual ads, media convergence, and the quest for ‘synergies’, has increasingly transformed all forms of culture into tools of marketing and promotion. What are the social, cultural, and political implications of these developments? How does advertising and ‘promotional culture’ affect the society in which we live, our value structures, belief systems, and our ideas about what constitutes ‘the good life’? Our primary objective is to critically explore contemporary advertising, as it connects to larger questions of society and culture. Our focus will NOT be on the ‘nuts and bolts’ of the advertising industry, nor will the course teach you how to create advertising campaigns, or how to design marketing strategies. Instead, we will draw upon different critical theories and empirical research methods, as a means of reflecting upon the broader social and cultural dimensions of advertising. We begin with a discussion of the relationship between advertising, promotional culture, and a social, economic, and cultural environment dominated by commodification. We then examine some of the dominant characteristics of post-modern advertising and promotional culture, using case studies of the representation of capitalism and the emerging phenomena of ‘green marketing’. In the latter half of the course, we broaden our focus beyond advertising texts to consider themes such as the marketing and promotion of pharmaceutical drugs, the commercialization of children’s culture, globalization, political advertising, consumer research and new media. _________________ This is a writing-intensive course. Students who began their degrees in Fall 2006 onwards must successfully complete at least two (W) courses, at least one of which must be upper division, preferably within the student’s discipline. It is strongly recommended that students take one (W) course as early as possible, preferably in their first 30 credits hours. Students are required to complete their first (W) course within their first 60 credit hours. †¦. over C ourse Format: The course is organized around a series of weekly themes that will be explored in lectures, readings and tutorial discussion. While there will be some overlap between the lectures, readings and tutorials, there will also be important material that is only covered in one or the other. In other words, you are expected to do the readings, attend the lectures and the tutorials to cover all the material that you will be tested upon and which you will have to draw upon in your research projects. Given that the course is writing-intensive, substantial tutorial time will be devoted to exercises and discussion designed to improve the writing skills of students. Participation in these exercises is a mandatory component of the course, thus students should be prepared to attend all tutorial meetings. The course is organized around a series of weekly themes that will be explored in lectures, readings and tutorial discussions. Required Readings: All course texts will be available on the course wiki. Grading: Grading is subject to confirmation in class. This is a tentative outline and subject to change. Creative Ad Project30% Final Paper55% Tutorial Participation15% The school expects that the grades awarded in this course will bear some reasonable relation to established university-wide practices with respect to both levels and distribution of grades. In addition, The School will follow Policy S10. 01 with respect to Academic Integrity, and Policies S10. 02, S10. 03 and S10. 04 as regards Student Discipline (note: as of May 1, 2009 the previous T10 series of policies covering Intellectual Honesty (T10. 02) and Academic Discipline (T10. 03) have been replaced with the new S10 series of policies). How to cite Cultural Dimensions In Advertising, Essay examples

Use of Antibiotics in Preventing Recurrent Acute for Effusion

Question: Write about theUse of Antibiotics in Preventing Recurrent Acute for Effusion. Answer: Introduction There is an extensive but controversial medical literature on medical resources needed to address problems related to otitis media. Recently, use of certain antibiotics in children suffering from otitis media has raised concerns from different quarters. Acute otitis media (AOM) can be addressed by use of antibiotics or surgical treatment; in which either treatment has certain benefits and demerits, warranting extensive debates and consultations before settling for one. For those who propose recurrent antibiotic treatment of recurrent AOM, the choice, timing and the period of antibiotic prophylaxis are to be resolved. There is uncertainty for otitis media effusion (OME) as to whether antibiotic offer placebo advantage (Rovers, Schilder, and Zielhuis, 2004 p. 22). The research is aimed at addressing these concerns hence the need for meta-analyses of antibiotics role in porphyries of recurrent AOM and OME treatment. Research questions that need to be satisfied include; 1. What is the magnitude of the effect of treatment of prophylactic a suppression of antibiotic of recurrent AOM? 2. what effect exists, if the details of using an antibiotic choice of timing, duration, and timing offer the highest beneficial effect. 3. What is a short-term magnitude of treatment effect if any, of OME resolution with antibiotic, 4. If OME effect exists in the short term. If there are long-term benefits. 5. If there is a presence of treatment effect with OME, what are the antibiotics optimal use, 6? Does the treatment vary for either condition by the characteristic of the patient that is known as the rates influencers of AOM such as group setting, age, socioeconomic status, and season of the year (Jacobs, Springer, and Crothers, 2001 p. 166)? Goals for Patients with Recurrent Otitis Media The main goals during treatment of recurrent otitis media include preventing of faster progression of infectious, addressing AOM complication, preventing hearing prevention deficits and promoting language development. The antibiotic studies use of either treatment of OME or prophylaxis of recruitment AOM were identified by MEDLINE during a 1996 search using refined searching that was linked with the otitis media phase. With one of the following terms; prospective, clinical trials, random models, placebo, statistical, placebos, the articles that were identified to help study more about the problems (Harrison, Tyler, Smith, and Findlay, 2004. P.45); the results confirmed that goals of treatment are as discussed herein. Methods Monographs, textbooks and current contents were searched. Use of randomly published controlled trials of the use of antibiotics in the AOM recurrent or OME was selected. The estimated effects of the submission and publication of studies with the findings that are null by the standard approach. The inclusion articles meeting criteria were obliged to conceal the source of authors, study location, publication and medication use. The results and methods sections were viewed independently, reviewed by reviewers who rated every article for ideal adherence characterized by a randomized controlled trial using a rating form that was standard (Hunink, Weinstein, Wittenberg etl 2014. P. 674). The reviewers also used an additional scoring sheet to rate the potential of the assessed report of confounding factors such age, race, status, duration, socioeconomic factors, disease, the previous therapy used for otitis media and the first episode of otitis media. Differences between reviewers accurate rating on specific items got solutions by the third blinded reviewer. The evaluation summary scores were rated. Articles that were selected were used for four meta-analyses separately. For sufficient outcome reports were used for more than analysis and the authors provided presented more data for more than one outcome. Meta-analyses addressed the use of antibiotics in the prophylaxis of recurrent AOM. Examining the episode frequency of meta-analyses. These go into the data present the number of patients per month. The outcome of treatment of OME was reported in this period; the outcome used the closest to a month after treatment. The patients in this group were in the unit of analysis. Free effusion for the patient to consider benefited treatment. The report that was similar with an exception the unit of outcome in the articles was cleared. A more conservative measure of the outcome the patient. The patient is one of the meta-analysis. Statistical Analysis Statistical analysis method DerSimonian analyses were used as well as Laird to calculate the differences in rates of treatment approximation and the effect at 95% confidence interval (Kemper, and Cohen, 2004.p 55). The random effect the random effect did not ensure homogeneity of the study population and incorporated different variability into the estimates. The effect summary statistics of effect using the approach is measured by terms of error within every study as the results are shown. Finding The findings of the meta-analysis offer support that is mixed for the use of antibiotics in the prophylaxis or treatment of OME and the recurrent AOM. Prophylaxis treatment works best for children with AOM intermittent with regards to prevention of AOM. The effect was limited by treatment requirement in which it showed ten children desirable treatment outcomes (Tan, Brainard, and Larkin, 2015 p. 455). However, the small RD is necessary to stand out given the nature of antitoxic and attraction risk (surgical treatment) There is lack of sufficient indication to recommend a particular antibiotic, although using sulfisoxazole seems to have better treatment outcomes compared with other antibiotics. The insufficient evidence fails to provide a recommendation on the treatment duration or the effect of the recurrence rates of AOM before therapy. For the case of OME, the antibiotics appear to be useful in a short course or short-term effusion clearance. With regard as to whether one considers it being the outcome of treatment. The effect is limited; however other patients need to be treated to improve the result in one of them and relatively short duration. In in a month or more after completion of treatment, there is no statistical improvement in comparison with control. Prevention of delays in language development is the major goal of OME treatment as well as general realization of developmental milestones that may be delayed by hearing deficits. Lack of effectiveness in treatment, in the long term, leads to questioning the value of antibiotic treatment with regards to its administration to achieve its goals. Language is not acquired in the short term interval. If there is persistence in the antibiotic treatment for a short duration, the goal may not be achieved. Additionally, recent studies conducted with placebo control tend to indicate lesser short-term antibiotic benefits. With meta-analysis, the findings reported herein rely on the concluded studies in the analysis. Two of the analyses suggest that those of the current otitis media and of OME with the outcome of measure involving the use of data that are not entirely independent. The results of the research could come more than once in one child since raw data was not available. However, since raw data was not available to address the question, and since methodology was not approached statistically through meta-analysis, type two errors were not excluded properly. Very few studies consider a few of the many potential factors that were confounded in the survey design. These analyses were also unable to address the question about how the characteristics of the patient influenced the effect of treatment. The lack of methodological rigor in the study included as indicated by the low-quality scores were considered as findings limitation. The study quality, however, shows that over and above assignment of patients randomly to treatment to be as considered findings limitation. The correction of the survey on the quality over and above the treatment of patients to be compared. Quantitative review The pooled showed findings an RD favoring the treatment of the antibiotic of 0.11 OAM episodes patient month (CI, 0.03 to 0.19 95%) the control in the group was 0.19. The pooled findings showed an RD favoring treatment of 0.11 events. The control rate groups were 0.19 (CI, 0.13 TO 0.26 95%). Three studies with 121 subjects in a total used crossover design. Excluding the crossover of the studies produced no change. Studies that used sulfisoxazole had a trend a better outcome (RD, 0.20;95%) (Young, Peppard, and Gottlieb, 2002.p 1218) OME Treatment, long tern common effects. The meta-analysis 4. In the meta-analysis, eight students were included 0f short-term to long-term outcome of the treatment of OME with antibiotics. Five studies had the results of favoring the treatment of antibiotic and three studies supported placebo, and two showed a small difference or no difference at all. One had CIs that zero was inclusive. In a pooled analysis it was found that little evidence for long-term or average benefit from antibiotic from antibiotic treatment of OME. When there was a division of studies by the use of ear or the patient as the outcome the results remained the same. With the patient the RD was o. o1 (95% CI, 0.06-0.08); with the ear was 0.12 (95% CI, 0.14 TO 0.26). Elimination on the study using the antibiotic of efficiency that is questionable (penicillin) did not affect the findings. Likewise, the division of the studies by the treatment duration. Summary and Recommendations Gens tends to produce treatment effects than the other antibiotics better; the statistical differences are not significant. Regarding the term of the therapy, no trend is the apparent or preexisting disease. These are with reason that the primary goal of OME treatment is preventing language or developmental delays due to the deficit of earing. The lack of long-term effectiveness results to one questioning the value of antibiotic treatment as it is currently administered in achieving this goal (Schneeweiss, 2007, p.144). In the short interval of time language is not acquired. If there is the persistence of antibiotic treatment for a short period only the goal my not achieved. Additionally, more recent studies and the studies conducted with controls placebo tended to show secondary benefits in short-term of the antibiotics. With any meta-analysis, the reported findings herein show on the studies in the analysis that was concluded. Three of the meta-analyses of those otitis media and OME that was recurrent with the ear as the measure of the outcome. The involvement of the use of the data that are not independent fully. The outcome under study occurred more than once in the same child. Since the used data was raw from the studies were unavailable, the statistical correction could not be appropriate and cloud not be the correction for this unknown dependency level (Thomas, and Witte, 2002, p. 510). The approach used is conservative in the correction for dependence would have resulted to narrow CIs. As the studies disagree on the duration of treatment, its possible that combining the results from all the studies may affect the difference between the results response curves at distinct points in time. However, since there was no raw data in the study to address the question and methodology did not exist to give the correction; as such straight-line was selected in response curves. Finally, there is currently no approach that is standard to calculating power for statistics summary obtainable through meta-analysis leading to exclusion of type II possibility in some of the null comparisons (Roberts, Rosenfeld, and Zeisel, 2004, p.240). The study design factors were very few that produces low scores. The limitation of the findings correction of the quality study over and above assignment is randomly given to patients to the treatment that is compared has not altered the results. When it has been done in the different meta-analysis and found no correlation between observed RD and qual ity (Welcome Trust Case Control Consortium, 2007 p. 663). Conclusion Antibiotics appear to have limited effect in treatment of OME but beneficial in treatment of recurrent otitis media and resolution of OME in the short run. OME long-term benefits have not been identified clearly. Most studies seem to be failing to consider their potential to produce usable recommendations. This has contributed to the inability to determine groups of patients that are most likely to benefit. There is uncertainty whether antibiotic treatment for otitis media with OME effusion offer any benefit over placebo. The meta-analysis in prophylaxis antibiotics of recurrent AOM and OME treatment attests to that. References Rovers, M.M., Schilder, A.G.,and Zielhuis, G.A. 2004. Otitis media.The Lancet,363(9407), pp.465-473. Klein, J.O., 2000. The burden of otitis media.Vaccine,19, pp.S2-S8. Jacobs, J., Springer, D.A. and Crothers, D., 2001. Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo-controlled trial.The Pediatric infectious disease journal,20(2), pp.177-183. Block, S.L., Hedrick, J., Harrison, C.J., Tyler, R., Smith, A., Findlay, R. and Keegan, E., 2004. Community-wide vaccination with the heptavalent pneumococcal conjugate significantly alters the microbiology of acute otitis media.The Pediatric infectious disease journal,23(9), pp.829-833. Lieberthal, A.S., Carroll, A.E., Chonmaitree, T., Ganiats, T.G., Hoberman, A., Jackson, M.A., Joffe, M.D., Miller, D.T., Rosenfeld, R.M., Sevilla, X.D. and Schwartz, R.H., 2013. The diagnosis and management of acute otitis media.Pediatrics,131(3), pp.e964-e999. Hunink, M.M., Weinstein, M.C., Wittenberg, E., Drummond, M.F., Pliskin, J.S., Wong, J.B. and Glasziou, P.P., 2014.Decision making in health and medicine: integrating evidence and values. Cambridge University Press. Degenhardt, B.F. and Kuchera, M.L., 2006. Osteopathic evaluation and manipulative treatment in reducing the morbidity of otitis media: a pilot study.The Journal of the American Osteopathic Association,106(6), pp.327-334. Tan, E., Brainard, A. and Larkin, G.L., 2015. Acceptability of the flipped classroom approach for in?house teaching in emergency medicine.Emergency Medicine Australasia,27(5), pp.453-459. Kemper, K.J. and Cohen, M., 2004. Ethics meet complementary and alternative medicine: new light on old principles. Laxminarayan, R., Duse, A., Wattal, C., Zaidi, A.K., Wertheim, H.F., Sumpradit, N., Vlieghe, E., Hara, G.L., Gould, I.M., Goossens, H. and Greko, C., 2013. Antibiotic resistancethe need for global solutions.The Lancet infectious diseases,13(12), pp.1057-1098. Marchisio, P., Nazzari, E., Torretta, S., Esposito, S. and Principi, N., 2014. Medical prevention of recurrent acute otitis media: an updated overview.Expert review of anti-infective therapy,12(5), pp.611-620. Roberts, J.E., Rosenfeld, R.M. and Zeisel, S.A., 2004. Otitis media and speech and language: a meta-analysis of prospective studies.Pediatrics,113(3), pp.e238-e248. Thomas, D.C. and Witte, J.S., 2002. Point: population stratification: a problem for case-control studies of candidate-gene associations?Cancer Epidemiology and Prevention Biomarkers,11(6), pp.505-512. Wellcome Trust Case Control Consortium, 2007. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.Nature,447(7145), p.661. Schneeweiss, S., 2007. Developments in post?marketing comparative effectiveness research.Clinical Pharmacology Therapeutics,82(2), pp.143-156. Young, T., Peppard, P.E. and Gottlieb, D.J., 2002. Epidemiology of obstructive sleep apnea: a population health perspective.American journal of respiratory and critical care medicine,165(9), pp.1217-1239.